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Monoclonal antibodies, against O1 serotype foot-and-mouth disease virus, from a natural bovine host, recognize similar antigenic features to those defined by the mouse.
TLDR
Although the bovine and murine anti-FMDV repertoires may not be identical these results support the recognition of similar antigenic features, including those of conformationally dependent epitopes. Expand
Effects of altering dietary essential fatty acids on requirements for non-steroidal anti-inflammatory drugs in patients with rheumatoid arthritis: a double blind placebo controlled study.
TLDR
It is suggested that EPO and EPO/fish oil produce a subjective improvement and allow some patients to reduce or stop treatment with NSAIDs, and there is no evidence that they act as disease modifying agents. Expand
Development of a reverse transcription polymerase chain reaction procedure for the detection of marine caliciviruses with potential application for nucleotide sequencing.
TLDR
The 1F/1R primer set has the advantage over the Hel1/Hel2 set in that it generates a larger PCR product for nucleotide sequence investigations and so provides greater opportunity for identifying molecular differences between the viruses. Expand
Exploring the "hair growth-wound healing connection": anagen phase promotes wound re-epithelialization.
TLDR
Gen profiling data reveal a clear correlation between the transcription of genes beneficial for wound healing and those upregulated during the anagen phase of the hair cycle in unwounded skin, and reveal numerous molecular correlates for further investigation. Expand
Direct evidence that PKCα positively regulates wound re‐epithelialization: correlation with changes in desmosomal adhesiveness
TLDR
This work presents the first direct evidence that protein kinase Cα (PKCα) plays an important role in regulating wound re‐epithelialization and suggests activation of PKCα as a new therapeutic strategy for non‐healing wounds. Expand
Genetic relationships between foot-and-mouth disease type Asia 1 viruses.
TLDR
A database of Asia 1 virus sequences has been established which will facilitate the rapid analysis of new outbreaks strains and show epidemiological links not previously evident. Expand
Pericytes in wound healing: friend or foe?
TLDR
This research presents a novel and scalable approach that combines cell reprograming, known as a ‘spatially aggregating immune response’, with a single dose of chemotherapy to treat eczema. Expand
A statistical analysis of murine incisional and excisional acute wound models
TLDR
It is reported that histology provides the least variable assessment of healing, and histology alone (not planimetry) is able to detect accelerated healing in a castrated mouse model, suggesting that use of wound (not animal) biological replicates is perfectly acceptable. Expand
A comparison of the genome organization of capripoxvirus with that of the orthopoxviruses
TLDR
The results show that the pattern of genomic conservation and variation between two poxvirus genera reflects the pattern within the orthopoxvirus genus but that, as observed previously, individual genes may not be present in genomic regions which are otherwise conserved in organization. Expand
Epithelial-to-Mesenchymal Stem Cell Transition in a Human Organ: Lessons from Lichen Planopilaris.
TLDR
It is shown that EMT also occurs within the bulge, the epithelial stem cell (eSC) niche of human scalp hair follicles, during the inflammatory permanent alopecia, lichen planopilaris, and that peroxisome proliferator-activated receptor-γ agonists are promising agents for suppressing and partially reversing EMT in human hair follicle eSCs ex vivo. Expand
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