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  • Influence
The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
TLDR
The task force concluded the term severe sepsis was redundant and updated definitions and clinical criteria should replace previous definitions, offer greater consistency for epidemiologic studies and clinical trials, and facilitate earlier recognition and more timely management of patients with sepsi or at risk of developing sepsic shock.
Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2016
TLDR
Although a significant number of aspects of care have relatively weak support, evidence-based recommendations regarding the acute management of sepsis and septic shock are the foundation of improved outcomes for these critically ill patients with high mortality.
Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016
TLDR
Although a significant number of aspects of care have relatively weak support, evidence-based recommendations regarding the acute management of sepsis and septic shock are the foundation of improved outcomes for these critically ill patients with high mortality.
Clinical practice guideline on diagnosis and treatment of hyponatraemia.
TLDR
The Clinical Practice Guideline on the diagnostic approach and treatment of hyponatraemia is developed as a joint venture of three societies representing specialists with a natural interest in hyponatonemia to obtain a common and holistic view.
Recommendations for the diagnosis and management of corticosteroid insufficiency in critically ill adult patients: Consensus statements from an international task force by the American College of
Objective:To develop consensus statements for the diagnosis and management of corticosteroid insufficiency in critically ill adult patients. Participants:A multidisciplinary, multispecialty task
A 3-level prognostic classification in septic shock based on cortisol levels and cortisol response to corticotropin.
TLDR
The data suggest that a short corticotropin test has a good prognostic value and could be helpful in identifying patients with septic shock at high risk for death.
Interleukin-6 Receptor Antagonists in Critically Ill Patients with Covid-19
TLDR
Treatment with the interleukin-6 receptor antagonists tocilizumab and sarilumab improved outcomes, including survival, in critically ill patients with Covid-19, an ongoing international, multifactorial, adaptive platform trial.
Hydrocortisone therapy for patients with septic shock.
TLDR
Hydrocortisone did not improve survival or reversal of shock in patients with septic shock, either overall or in patients who did not have a response to corticotropin, although hydroc Cortisone hastened reversal ofshock in patients in whom shock was reversed.
Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock 2012
TLDR
An update to the “Surviving Sepsis Campaign Guidelines for Management of Severe Sepsis and Septic Shock,” last published in 2008 is provided.
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