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Waist circumference percentiles in nationally representative samples of African-American, European-American, and Mexican-American children and adolescents.
Age-, sex-, and ethnicity-specific WC percentiles are available for US children and adolescents and can be used as an assessment tool that could impact public health recommendations and suggest concern with respect to high WC values among certain ethnic groups. Expand
Caloric Restriction Delays Disease Onset and Mortality in Rhesus Monkeys
Findings of a 20-year longitudinal adult-onset CR study in rhesus monkeys aimed at filling this critical gap in aging research demonstrate that CR slows aging in a primate species. Expand
Estimating African American admixture proportions by use of population-specific alleles.
Significant nonrandom association between two markers located 22 cM apart (FY-null and AT3) is detected, most likely due to admixture linkage disequilibrium created in the interbreeding of the two parental populations, emphasize the importance of admixed populations as a useful resource for mapping traits with different prevalence in two parental population. Expand
Years of life lost due to obesity.
Obesity appears to lessen life expectancy markedly, especially among younger adults, and Marked race and sex differences were observed in estimated YLL. Expand
Body mass index as a measure of adiposity among children and adolescents: a validation study.
The results support the use of BMI as a fatness measure in groups of children and adolescents, although interpretation should be cautious when comparing BMI across groups that differ in age or when predicting a specific individual's TBF or PBF. Expand
Microarray data analysis: from disarray to consolidation and consensus
The y- axis label for Figure 1d was incorrect and the correct y-axis label should be . Expand
A mixture model approach for the analysis of microarray gene expression data
Microarrays have emerged as powerful tools allowing investigators to assess the expression of thousands of genes in different tissues and organisms. Statistical treatment of the resulting dataExpand
Impact of caloric restriction on health and survival in rhesus monkeys from the NIA study
A separation between health effects, morbidity and mortality, and similar to what has been shown in rodents, study design, husbandry and diet composition may strongly affect the life-prolonging effect of CR in a long-lived nonhuman primate is suggested. Expand
Effects of low-dose, controlled-release, phentermine plus topiramate combination on weight and associated comorbidities in overweight and obese adults (CONQUER): a randomised, placebo-controlled,
The efficacy and safety of two doses of phentermine plus topiramate controlled-release combination as an adjunct to diet and lifestyle modification for weight loss and metabolic risk reduction in individuals who were overweight and obese, with two or more risk factors is assessed. Expand
Primary care physicians' attitudes about obesity and its treatment.
Primary care physicians view obesity as largely a behavioral problem and share the authors' broader society's negative stereotypes about the personal attributes of obese persons but view obesity treatment as less effective than treatment of most other chronic conditions. Expand