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Hydrogen peroxide and the proliferation of BHK-21 cells.
It is argued that critical balances between intracellular levels of both H2O2 and glutathione are of significance in relation both to growth stimulation and inhibition.
Endogenously generated active oxygen species and cellular glutathione levels in relation to BHK-21 cell proliferation.
During the normal growth phase cellular levels of GSH actually decline although this effect can be partly reversed by N-acetylcysteine and by mercaptosuccinate which also impair proliferation of these cells.
Hydrogen peroxide in relation to proliferation and apoptosis in BHK-21 hamster fibroblasts.
Addition of H2O2 at 100 microM, or 1 mM, to the culture medium of BHK-21 fibroblasts results in increased intracellular levels of H2O2. Whilst exposure of BHK-21 cells to lower levels of H2O2 (1…
Effects of beta-carotene, flavonoid quercitin and quinacrine on cell proliferation and lipid peroxidation breakdown products in BHK-21 cells.
- D. Alliangana
- BiologyEast African medical journal
- 1 November 1996
Quinacrine an inhibitor of phospholipase A2 activity not only abated the decline in cellular lipid peroxidation breakdown products but also abridged the rate of cell proliferation.
Thermal balance in the crested guinea fowl