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Birmingham Vasculitis Activity Score (BVAS) in systemic necrotizing vasculitis.
The continuing morbidity of patients with vasculitis, despite the improved prognosis with aggressive therapy, underlines the need for accurate disease assessment. We have devised a clinical index ofExpand
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Development and initial validation of the Vasculitis Damage Index for the standardized clinical assessment of damage in the systemic vasculitides.
OBJECTIVE To develop and validate the Vasculitis Damage Index (VDI) for the standardized clinical assessment of damage in the systemic vasculitides. METHODS Using a nominal group consensusExpand
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Intravenous immunoglobulin for ANCA-associated systemic vasculitis with persistent disease activity.
Intravenous immunoglobulin (IVIg) is a potential alternative treatment for anti-neutrophil cytoplasm antibody (ANCA)-associated systemic vasculitis (AASV) with less toxicity than conventionalExpand
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Enabling the genomic revolution in Africa
H3Africa is developing capacity for health-related genomics research in Africa Our understanding of genome biology, genomics, and disease, and even human history, has advanced tremendously with theExpand
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Copy number of FCGR3B, which is associated with systemic lupus erythematosus, correlates with protein expression and immune complex uptake
Copy number (CN) variation (CNV) has been shown to be common in regions of the genome coding for immune-related genes, and thus impacts upon polygenic autoimmunity. Low CN of FCGR3B has recently beenExpand
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Prevalence of Chronic Kidney Disease in Hypertensive Patients in Ghana
Chronic kidney disease (CKD) is common in tropical Africa although there are few data on the prevalence of this disorder. Therefore we initiated a multicenter screening study to identify theExpand
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Interleukin-2 receptor monoclonal antibodies in renal transplantation: meta-analysis of randomised trials
Abstract Objective: To study the effect of interleukin-2 receptor monoclonal antibodies on acute rejection episodes, graft loss, deaths, and rate of infection and malignancy in patients with renalExpand
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Immunosuppression for progressive membranous nephropathy: a UK randomised controlled trial
Summary Background Membranous nephropathy leads to end-stage renal disease in more than 20% of patients. Although immunosuppressive therapy benefits some patients, trial evidence for the subset ofExpand
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The value of pulse cyclophosphamide in ANCA-associated vasculitis: meta-analysis and critical review.
BACKGROUND The study aimed at studying efficacy and adverse effects of pulse cyclophosphamide (pCyc) treatment and to compare it to continuous cyclophosphamide (cCyc) for induction of remission inExpand
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In 3 years seventeen patients presented to one unit with renal failure associated with the use of non-steroidal anti-inflammatory drugs (NSAID). Seven patients presented with acute renal failure, inExpand
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