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- Publications
- Influence
Influence of glutathione S-transferase polymorphisms on type-2 diabetes mellitus risk.
- M. A. Amer, M. Ghattas, D. Abo-Elmatty, S. Abou-El-Ela
- Medicine
- Genetics and molecular research : GMR
- 31 October 2011
Glutathione S-transferase (GST) protects cells against oxidative stress. We evaluated the effect of genetic polymorphisms of the GST gene family on the risk of developing type-2 diabetes mellitus and… Expand
Cisplatin-induced cardiotoxicity: Mechanisms and cardioprotective strategies.
- El-Sayed E. El-Awady, Y. Moustafa, D. Abo-Elmatty, A. Radwan
- Chemistry, Medicine
- European journal of pharmacology
- 10 January 2011
Increased oxidative stress and apoptosis have been implicated in the cardiotoxicity that limits the clinical use of cisplatin as an anti-tumoral drug. Our study was conducted to evaluate the… Expand
Acetyl-l-carnitine and α-lipoic acid affect rotenone-induced damage in nigral dopaminergic neurons of rat brain, implication for Parkinson's disease therapy
- S. Zaitone, D. Abo-Elmatty, A. A. Shaalan
- Chemistry, Medicine
- Pharmacology Biochemistry and Behavior
- 31 January 2012
Although the mechanisms of neurodegeneration in Parkinson's disease are not fully understood, mitochondrial dysfunction, oxidative stress and environmental toxins may be involved. The current… Expand
Piracetam and vinpocetine ameliorate rotenone-induced Parkinsonism in rats
- S. Zaitone, D. Abo-Elmatty, S. Elshazly
- Medicine
- Indian journal of pharmacology
- 1 November 2012
Objective: To evaluate the neuroprotective effect of the nootropic drugs, piracetam (PIR) and vinpocetine (VIN), in rotenone-induced Parkinsonism in rats. Materials and Methods: Sixty male rats were… Expand
Bacterial Community Analyses of Two Red Sea Sponges
Red Sea sponges offer potential as sources of novel drugs and bioactive compounds. Sponges harbor diverse and abundant prokaryotic communities. The diversity of Egyptian sponge-associated bacterial… Expand
Effect of metabolites isolated from Cuscutapedicellata on high fat diet-fed rats
- Salwa H. Zekry, D. Abo-Elmatty, +4 authors S. Ahmed
- Chemistry
- Medicinal Chemistry Research
- 1 May 2015
AbstractThe aim of the present study was to determine if Cuscuta pedicellata extract has an effect on body weight and serum lipid profile in the HFD-fed rats’ animal model. The ethanol extract of C.… Expand
C-reactive protein 1059G/C gene polymorphism, C-reactive protein levels and acute myocardial infarction
- M. Ghattas, D. Abo-Elmatty, Azza Z El-Eraki
- Medicine
- Journal of cardiovascular medicine
- 1 November 2012
Aims High-sensitivity C-reactive protein (hs-CRP) is an inflammatory marker, predicting the occurrence of acute myocardial infarction (AMI). Genetic predisposition to high baseline CRP might account… Expand
Evaluation of glutathione S-transferase P1 genetic variants affecting type-2 diabetes susceptibility and glycemic control
- M. A. Amer, M. Ghattas, D. Abo-Elmatty, Soad H. Abou-El-Ela
- Medicine
- Archives of medical science : AMS
- 8 September 2012
Introduction Type 2 diabetes mellitus (T2DM) is associated with increased production of reactive oxygen species and a reduction in antioxidant defenses leading to oxidative stress. Glutathione… Expand
Atorvastatin restores the balance between pro-inflammatory and anti-inflammatory mediators in rats with acute myocardial infarction.
- M. Tawfik, M. H. Ghattas, D. Abo-Elmatty, N. A. Abdel-Aziz
- Medicine
- European review for medical and pharmacological…
- 1 June 2010
BACKGROUND
Pro- and anti-inflammatory cytokines play a major role in the development of acute myocardial infarction (AMI). This paper tests the hypothesis that atorvastatin may attenuate the severity… Expand
Induction of sub-G0 arrest and apoptosis by seed extract of Moringa peregrina (Forssk.) Fiori in cervical and prostate cancer cell lines.
- M. Abou-Hashem, D. Abo-Elmatty, N. Mesbah, Ahmed Mohamed Abd El-Mawgoud
- Chemistry, Medicine
- Journal of integrative medicine
- 1 November 2019
OBJECTIVE
This study investigated cytotoxicity and induction of apoptosis in human cervical cancer cells (HELA) and prostate cancer cells (PC-3) using the most active fraction of Moringa peregrina… Expand