Are subordinates always stressed? a comparative analysis of rank differences in cortisol levels among primates
- D. Abbott, E. Keverne, R. Sapolsky
- BiologyHormones and Behavior
- 31 January 2003
Androgen excess fetal programming of female reproduction: a developmental aetiology for polycystic ovary syndrome?
- D. Abbott, D. K. Barnett, C. M. Bruns, D. Dumesic
- Biology, MedicineHuman Reproduction Update
- 1 July 2005
Animal models that mimic fetal androgen excess may provide unique insight into the origins of the PCOS syndrome, and the prenatally androgenized female rhesus monkey shows particular relevance to PCOS.
Behavioral and physiological suppression of fertility in subordinate marmoset monkeys
- D. Abbott
- BiologyAmerican Journal of Primatology
- 1984
In well‐established families, a familiarity or inbreeding taboo restricted reproduction among otherwise fertile offspring, however, only one daughter ovulated in any family, and in up to 50% of family groups, all daughters were inhibited from ovulating.
Aspects of common marmoset basic biology and life history important for biomedical research.
- D. Abbott, D. K. Barnett, R. Colman, M. E. Yamamoto, N. Schultz-Darken
- BiologyComparative medicine
- 1 August 2003
Important marmoset attributes that are particularly relevant for biomedical research, including reproduction, neurobiology, immunology, endocrine signaling, obesity and aging, in addition to fetal and postnatal development are described.
Molecular abnormalities in oocytes from women with polycystic ovary syndrome revealed by microarray analysis.
- J. Wood, D. Dumesic, D. Abbott, J. Strauss
- BiologyJournal of Clinical Endocrinology and Metabolism
- 1 February 2007
Promoter analysis suggests that androgens and other activators of nuclear receptors may play a role in differential gene expression in the PCOS oocyte and annotation of the differentially expressed genes suggests that defects in meiosis or early embryonic development may contribute to reduced developmental competency of PCos oocytes.
Developmental origin of polycystic ovary syndrome - a hypothesis.
- D. Abbott, D. Dumesic, S. Franks
- Biology, MedicineJournal of Endocrinology
- 1 July 2002
It is proposed that the clinical and biochemical features of PCOS can arise as a consequence of genetically determined hypersecretion of androgens by the ovary during, or very likely long before, puberty, and a unifying, 'linear' model is suggested to explain the aetiology of the heterogeneous phenotype.
Physical, hormonal and behavioural aspects of sexual development in the marmoset monkey, Callithrix jacchus.
Measurements of growth, plasma progesterone and testosterone levels, and copulatory behaviour were obtained from captive marmosets from birth until 600-800 days of age, finding that in peer groups, only the dominant female became pregnant, because subordinate females failed to ovulate.
Reproduction in captive common marmosets (Callithrix jacchus).
- S. Tardif, D. Smucny, D. Abbott, K. Mansfield, N. Schultz-Darken, M. E. Yamamoto
- BiologyComparative medicine
- 1 August 2003
An overview of reproduction in the common marmoset is provided, including basic reproductive life history, lactation and weaning, social housing requirements, and common problems encountered in the captive breeding of this species.
Environmental Factors and Puberty Timing: Expert Panel Research Needs
- G. B. Buck Louis, L. Gray, S. Euling
- MedicinePediatrics
- 1 February 2008
The panel concluded that available experimental animal and human data support a possible role of endocrine-disrupting chemicals and body size in relation to alterations in pubertal onset and progression in boys and girls.
Social suppression of ovarian cyclicity in captive and wild colonies of naked mole-rats, Heterocephalus glaber.
- C. G. Faulkes, D. Abbott, J. Jarvis
- BiologyJournal of Reproduction and Fertility
- 1 March 1990
The results suggest that ovulation is suppressed in subordinate non-breeding female naked mole-rats in captive and wild colonies, and show that plasma LH concentrations are significantly lower in these non- breeding females.
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