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Pharmacokinetics of rebaudioside A and stevioside after single oral doses in healthy men.
This randomized, double-blind, cross-over study assessed the comparative pharmacokinetics of steviol and steviol glucuronide following single oral doses of rebaudioside A and stevioside in healthyExpand
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Pharmacokinetic Assessment of Drug‐Drug Interactions of Isavuconazole With the Immunosuppressants Cyclosporine, Mycophenolic Acid, Prednisolone, Sirolimus, and Tacrolimus in Healthy Adults
This report summarizes phase 1 studies that evaluated pharmacokinetic interactions between the novel triazole antifungal agent isavuconazole and the immunosuppressants cyclosporine, mycophenolicExpand
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A semiparametric model for accurate camera response function modeling and exposure estimation from comparametric data
A fundamentally new approach that accurately estimates the camera response function from comparametric data, i.e., pixel data from two differently exposed images over a common field of view, isExpand
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Mass Balance, Metabolite Profile, and In Vitro-In Vivo Comparison of Clearance Pathways of Deleobuvir, a Hepatitis C Virus Polymerase Inhibitor
  • L. Chen, J. Sabo, +6 authors R. Sane
  • Medicine, Biology
  • Antimicrobial Agents and Chemotherapy
  • 13 October 2014
ABSTRACT The pharmacokinetics, mass balance, and metabolism of deleobuvir, a hepatitis C virus (HCV) polymerase inhibitor, were assessed in healthy subjects following a single oral dose of 800 mg ofExpand
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Placebo-Controlled, Double-Blind, First-In-Human, Ascending Single Dose and Multiple Dose, Healthy Subject Study Of Intravenous-Administered SelG1, a Humanized Anti-P-Selectin Antibody In Development
SelG1 is a humanized anti-P-selectin monoclonal antibody being developed as a treatment for sickle cell disease (SCD). Extensive data have been published that suggest a pivotal role for P-selectin inExpand
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Mass Balance and Metabolite Profiling of Steady-State Faldaprevir, a Hepatitis C Virus NS3/4 Protease Inhibitor, in Healthy Male Subjects
  • L. Chen, P. Rose, +6 authors Y. Li
  • Medicine, Chemistry
  • Antimicrobial Agents and Chemotherapy
  • 10 February 2014
ABSTRACT The pharmacokinetics, mass balance, and metabolite profiles of faldaprevir, a selective peptide-mimetic hepatitis C virus NS3/NS4 protease inhibitor, were assessed at steady state in 7Expand
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