D William Cameron

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A set of scenarios is a useful way to capture many aspects of the requirements of a system. Use Case Maps are a method for scenario capture which is good for describing multiple scenarios, including scenario interactions, for developing an architecture, and for analysing architectural alternatives. However once a component architecture is determined ,(More)
To determine the frequency and risk factors for female to male sexual transmission of human immunodeficiency virus type 1 (HIV-1), a prospective study was carried out in 422 men who had acquired a sexually transmitted disease (STD) from a group of prostitutes with a prevalence of HIV-1 infection of 85%. The initial seroprevalence of HIV among the men was(More)
Condom use was assessed after a programme of education about the acquired immunodeficiency syndrome and a condom distribution programme in a well-characterised prostitute population in Nairobi. Women received their education at group meetings (barazas) and at individual counselling sessions during which they were given the results of serological tests for(More)
BACKGROUND Ritonavir is a potent, orally bioavailable inhibitor of HIV-1 protease. We undertook an international, multicentre, randomised, double-blind, placebo-controlled trial of ritonavir in patients with HIV-1 infection and CD4-lymphocyte counts of 100 cells/microL or less, who had previously been treated with antiretroviral drugs. METHODS 1090(More)
To evaluate the performance of a software design one must create a model of the software, together with the execution platform and configuration. Assuming that the "platform": (processors, networks, and operating systems) are specified by the designer, a good "configuration" (the allocation of tasks to processors, priorities, and other aspects of the(More)
Incidence of human breast cancer (HBC) varies geographically, but to date no environmental factor has explained this variation. Previously, we reported a 44% reduction in the incidence of breast cancer in women fully immunosuppressed following organ transplantation (Stewart et al (1995) Lancet 346: 796-798). In mice infected with the mouse mammary tumour(More)
BACKGROUND Community-acquired pneumonia (CAP) is a leading cause of morbidity and mortality. CAP can trigger acute cardiac events. We sought to determine the incidence of major cardiac complications in CAP patients to characterize the magnitude of this problem. METHODS AND FINDINGS Two investigators searched MEDLINE, Scopus, and EMBASE for observational(More)
BACKGROUND Tuberculosis (TB) is the most common opportunistic infection in HIV-infected adults in developing countries. Isoniazid (INH) is recommended for treatment of latent TB infection, however non-adherence is common. The purpose of this study was to apply in-house prepared isoniazid (INH) urine test strips in a clinical setting, and identify predictors(More)
The time it takes to develop telecommunication standards must be reduced to allow companies to get features to the market faster. In order to achieve this objective, a process based on the combination of a set of modeling techniques has been proposed by Nortel Networks in the context of the Wireless Intelligent Network (WIN) standard development. This(More)