The crucial early stages of amyloid growth, in which normally soluble proteins are converted into fibrillar nanostructures, are challenging to study using conventional techniques yet are critical to the protein aggregation phenomena implicated in many common pathologies. As with all nucleation and growth phenomena, it is difficult to track individual nuclei… (More)
We consider the spatial dependence of filamentous protein self-assembly. Through studying the cases where the spreading of aggregated material is dominated either by diffusion or by growth, we derive analytical results for the spatial evolution of filamentous protein aggregation, which we validate against Monte Carlo simulations. Moreover, we compare the… (More)
As11 and em11 form an emulated PDP-11* environment which can be used on UNIX † systems to design and develop simple PDP-11 assembly language programs. The emulated PDP-11 includes 16K bytes of store, a screen, a keyboard, a line printer, and two random access disks. Just as Modula-2 uses standard suffixes such as .def and .mod to identify files as belonging… (More)
Rhodococcus sp. strain PML026 produces an array of trehalolipid biosurfactant compounds in order to utilize hydrophobic carbon sources, such as oils and alkanes. Here, we report the high-quality draft genome sequence of this strain, which has a total length of 5,168,404 bp containing 4,835 protein-coding sequences, 12 rRNAs, and 45 tRNAs.
ML092740597 NOTE These procedures were formerly issued by the Office of State and Tribal Programs (STP). Any changes to the procedure are the responsibility of the FSME Procedure Contact as of October 1, 2006. Copies of FSME procedures are available through the NRC web site.