D W Swinkels

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BACKGROUND AND PURPOSE Anaemia of chronic disease is characterized by impaired erythropoiesis due to functional iron deficiency, often caused by excessive hepcidin. Lexaptepid pegol, a pegylated structured l-oligoribonucleotide, binds and inactivates hepcidin. EXPERIMENTAL APPROACH We conducted a placebo-controlled study on the safety, pharmacokinetics(More)
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