D. W. Chandler

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Minimum audible movement angles (MAMAs) were measured in the horizontal plane for four normal-hearing adult subjects in a darkened anechoic chamber. On each trial, a single stimulus was presented, and the subject had to say whether it came from a stationary loudspeaker or from a loudspeaker that was moving at a constant angular velocity around him.(More)
OBJECTIVE A link between serum testosterone and aggressive behavior, which has been demonstrated in numerous animal studies and suggested in several studies of adult men, has never been investigated in children before the time of puberty. METHOD We measured serum testosterone, sex hormone binding globulin (SHBG), dehydroepiandrosterone (DHEA), and(More)
Sex determination in Drosophila melanogaster is regulated by a cascade of splicing factors which direct the sex-specific expression of gene products needed for male and female differentiation. The splicing factor TRA-2 affects sex-specific splicing of multiple pre-mRNAs involved in sexual differentiation. The tra-2 gene itself expresses a complex set of(More)
The preferred sense of product molecule rotation (clockwise or counterclockwise) in a bimolecular collision system has been measured. Rotationally inelastic collisions of nitric oxide (NO) molecules with Ar atoms were studied by combining crossed molecular beams, circularly polarized resonant multiphoton ionization probing, and velocity-mapped ion imaging(More)
BACKGROUND We analyzed the potential of abiraterone acetate (henceforth abiraterone) to reduce androgen levels below lower limits of quantification (LLOQ) and explored the association with changes in PSA decline in metastatic castration-resistant prostate cancer (mCRPC) patients. METHODS COU-AA-301 is a 2:1 randomized, double-blind, placebo-controlled(More)
The differential cross section for the H + D(2) --> HD + D reaction has been measured using a technique called reaction product imaging. In this experiment, a photolytically produced beam of hydrogen (H) atoms crossed a beam of cold deuterium (D(2)) molecules. Product D atoms were ionized at the intersection of the two particle beams and accelerated toward(More)
  • P L Houston, B R Cosofret, A Dixit, S M Dylewski, J D Geiser, J A Mueller +5 others
  • 2001
This paper briefly reviews recent progress in product imaging studies of photodissociation and bimolecular reaction dynamics. The SO 2 + h SO(3 (-) + O(3 P 2) channel in the ultraviolet photodissociation of sulfur dioxide at photolysis wavelengths between 202 and 207 nm has been studied using resonance-enhanced multiphoton ionization with time-of-flight(More)
In vitro transcription of cleaved SV40 DNA with calf thymus RNA polymerase reveals a discrete transcript. The pattern of resistance to the inhibitor alpha-amanitin identifies the RNA as a product of RNA polymerase III transcription. The RNA is shown to initiate artificially near a DNA terminus created by cleavage and to terminate specifically near a cluster(More)
A radioimmunoassay method for the measurement of plasma levels of 18-hydroxy-11 -deoxycorticosterone (18 -OH-DOC) has been developed. The antiserum against 18-OH-DOC was produced in rabbits immunized against 18-OH-DOC-3-oxime-bovine serum albumin. Plasma (1-2 ml) was extracted with dichloromethane and chromatographed on paper. The purified extracts were(More)
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