D. Thompson

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This paper presents a framework for the design of a haptic-based medical ultrasound training simulator. The proposed simulator is composed of a PHANToM haptic device and a modular software package that allows for visual feedback and kinesthetic interactions between an operator and multimodality image databases. The system provides real-time ultrasound(More)
Over the last decade object-oriented development methods and techniques have gained rapid acceptance in many areas, for example Graphi-cal User Interfaces and Network Programming. Currently there are two major standard archi-tectures available to support Distributed Object-Oriented Programming: the Object Management Group's Common Object Request Broker(More)
As sexual transmission of human immunodeficiency virus-1 (HIV-1) occurs via the mucosa, an ideal HIV-1 vaccine should induce both mucosal and systemic immunity. We therefore sought to evaluate the induction of mucosal responses using a DNA env prime-gp120 protein boost approach in which sequential nasal and parenteral protein administration was performed(More)
PHR [PAM (protein associated with Myc)-HIW (Highwire)-RPM-1 (regulator of presynaptic morphology 1)] proteins are conserved, large multi-domain E3 ubiquitin ligases with modular architecture. PHR proteins presynaptically control synaptic growth and axon guidance and postsynaptically regulate endocytosis of glutamate receptors. Dysfunction of neuronal(More)
Background: Due to Lesotho's high adult HIV prevalence (23%), considerable resources have been allocated to the HIV/AIDS response, while resources for non-communicable diseases have lagged. Since November 2011, the Elizabeth Glaser Pediatric AIDS Foundation (EGPAF) has supported Lesotho Ministry of Health to roll out Family Health Days (FHDs), an innovative(More)
We present a novel haptic-based simulator for training radiology residents and sonographers. The system consists of a force feedback haptic device that interacts in real-time with registered 3D multi-modality data sets of a subject anatomy, rendered and sliced simultaneously. The proposed system allows to develop radiology expertise with minimum practice on(More)