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We prove local in time well-posedness for the Zakharov system in two space dimensions with large initial data in L 2 × H −1/2 × H −3/2. This is the space of optimal regularity in the sense that the data-to-solution map fails to be smooth at the origin for any rougher pair of spaces in the L 2-based Sobolev scale. Moreover, it is a natural space for the(More)
Studies in the United States (US) have reported varying treatment and survival for patients with high grade glioma from different ethnic groups. This study investigates for the first time whether differences also exist in the United Kingdom (UK). This population-based cohort study used cancer registration data for 4,845 patients diagnosed in South East(More)
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