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Clotting within the dialyser is one of the most significant clinical parameters of biocompatibility. A study was designed to evaluate the biocompatibility of two different dialysis membranes (cuprophane and polyacrylonitrile) during therapy with conventional heparin. Transient leukopenia during cuprophane but not during polyacrylonitrile haemodialysis was(More)
Hemodialysis is not an absolute prerequisite for the formation of beta 2-microglobulin amyloidosis, but it enhances the progression of this complication related to long-standing renal failure. Thus the clearance and turnover of beta 2-microglobulin seems to play a major role in this disease. In a prospective multicenter study the beta 2-microglobulin(More)
Two methods are described by which primer molecules like UpU and oligodeoxythymidylates can be coupled with high efficiency to an insoluble polymer, like hydroxypropylated Sephadex G-50, by one covalent linkage. In one procedure aliphatic dicarboxylic dichlorides (e.g. adipoyl dichloride) are used to serve as spacers of variable length and for anchoring the(More)
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