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A contrived play group procedure was utilized to examine the behavioral and social-cognitive correlates of reactive aggression, proactive aggression, and victimization via peers. Eleven play groups, each of which consisted of six familiar African-American 8-year-old boys, met for 45-min sessions on five consecutive days. Social-cognitive interviews were(More)
This investigation utilized a contrived play group procedure to examine the behavioral patterns leading to chronic victimization by peers in middle childhood. 30 play groups, each of which consisted of 6 unacquainted African-American 6-year-old or 8-year-old boys, met for 45-min sessions on 5 consecutive days. Play group interactions were videotaped and(More)
Whole-cell electrophysiological studies suggest that sympathetic nerve alpha-2 adrenergic receptors are coupled to voltage-dependent N-type calcium channels through the Gi family of proteins to inhibit neurotransmitter release. Because most nerve terminals are too small for direct electrophysiological recordings, the aim of this study was to examine the(More)
This study reports a cross-sectional investigation of the behavioral and academic correlates of victimization in Chinese children's peer groups. The participants were 296 children (161 boys and 135 girls; mean age = 11.5 years) from Tianjin, China. Multi-informant assessments (peer nominations, teacher ratings, and self-reports) of peer victimization,(More)
The purpose of this study was to determine whether a decrease in cyclic AMP accumulation mediates the inhibition of norepinephrine release in response to alpha-2 adrenergic receptor activation in cultured rat superior cervical ganglion cells. Superior cervical ganglia from neonatal rats were dissociated and cultured on collagen-coated plastic strips.(More)
Phenylephrine increased [3H]norepinephrine efflux and accumulation of cyclic AMP in cultured rat superior cervical ganglion cells superfused with Tyrode's solution. The purpose of this study was to determine the mechanism and relationship between these two events. Electrical stimulation (1-2 Hz), potassium chloride (50 mM), and the preferential alpha(More)
Neuropeptide Y has been reported to inhibit the release of the adrenergic transmitter from sympathetic nerves in many tissues. The purpose of this study was to determine the mechanism of the inhibitory effect of neuropeptide Y on the release of the adrenergic transmitter in cultured superior cervical ganglion cells prelabeled with tritiated norepinephrine.(More)
Costello syndrome is a rare rasopathy resulting from germline mutations of the proto-oncogene HRAS. Its phenotype includes severe failure-to-thrive, cardiac abnormalities, a predisposition to benign and malignant tumors, hypotonia, and developmental delay. Costello syndrome is associated with cognitive impairment, including intellectual functioning(More)
Costello syndrome (CS) is a rare genetic disorder caused by germline mutations in the HRAS proto-oncogene which belongs to the family of syndromes called rasopathies. HRAS plays a key role in synaptic long-term potentiation (LTP) and memory formation. Prior research has found impaired recall memory in CS despite enhancement in LTP that would predict memory(More)
Prior empirical work has documented that the dynamics of social standing can play a critical role in the perpetration and receipt of aggression during adolescence. Recently, investigators have emphasized the emergence of new, electronic modalities for aggressive acts. Our longitudinal project therefore considered electronic forms of aggression and(More)