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1. In acute experimental hydronephrosis chloride retention occurs as well as retention of water, urea, and phenolsulfonephthalein. 2. If both water and chlorides are retained there may be no appreciable rise in the plasma chloride content. 3. When chlorides are retained, but not water, the chloride content of the plasma rises strikingly. 4. After the… (More)
In a previous paper (Keith and Pulford) we described a method for producing experimental hydronephrosis, which permitted the study of renal function in this condition for periods varying from weeks to months. The method used was the partial obstruction of both ureters near the ureteropelvic juncture. After a thorough functional study of hydronephrosis thus… (More)