D Scholtens

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PURPOSE To prospectively evaluate the quality of life (QOL) before, at completion, and after therapy for patients receiving an accelerated fractionation schedule of radiotherapy for advanced, unresectable non-small-cell lung cancer in a Phase II multi-institutional trial. METHODS AND MATERIALS The Functional Assessment of Cancer Therapy-Lung (FACT-L)(More)
580 Background: Several features have been identified in DCIS diagnosed by core biopsy (DCIS-core) which predict the presence of invasive carcinoma (IC) in the surgical specimen. However, these have not been combined into a model to predict which patients with DCIS-core will be found to have IC on excision, a tool that will be useful both for clinical(More)
S1 Assessing prognosis for early breast cancer: clinical versus genetic profiles GN Hortobagyi Department of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA Breast Cancer Research 2007, 9(Suppl 1):S1 (doi: 10.1186/bcr1684) Since the introduction of systemic adjuvant chemotherapy (ACT) and endocrine therapy in the(More)
137 Background: IBTR after breast conservation encompasses true recurrence (TR) and new primary cancer (NP). No clear criteria distinguish TR from NP, but there is agreement that NP tumors have better outcomes than TR. Prior studies have used distance of IBTR from index cancer (IC), time to IBTR, histological, immunohistochemical (IHC) and genetic(More)
AIM We hypothesised that some of the genetic risk for gestational diabetes (GDM) is due to the fetal genome affecting maternal glucose concentrations. Previously, we found associations between fetal IGF2 gene variants and maternal glucose concentrations in late pregnancy. METHODS In the present study, we tested associations between SNP alleles from 15(More)
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