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Viruses are a common threat to cellular life, not the least to bacteria and archaea who constitute the majority of life on Earth. Consequently, a variety of mechanisms to resist virus infection has evolved. A recent discovery is the adaptive immune system in prokaryotes, a type of system previously thought to be present only in vertebrates. The system,(More)
Source and Description: Direct genomic sequencing revealed a C to A polymorphism 65 nucleotides in front of exon 19 (nucleotide 3601-65) of the CFTR gene that is causative defective in cystic fibrosis (CF) (1). This polymorphism generates cleavage sites for Hinfl and MboII and is useful as an intragenic marker for the assignment of marker haplotypes of(More)