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- Publications
- Influence
Identical mutation in a novel retinal gene causes progressive rod-cone degeneration in dogs and retinitis pigmentosa in humans.
- B. Zangerl, Orly Goldstein, +9 authors G. Aguirre
- Biology, Medicine
- Genomics
- 1 November 2006
Progressive rod-cone degeneration (prcd) is a late-onset, autosomal recessive photoreceptor degeneration of dogs and a homolog for some forms of human retinitis pigmentosa (RP). Previously, the… Expand
A protein engineering study of the role of aspartate 158 in the catalytic mechanism of papain.
- R. Ménard, H. Khouri, +7 authors A. C. Storer
- Chemistry, Medicine
- Biochemistry
- 17 July 1990
The controversy concerning the various suggested roles for the side chain of Asp158 in the active site of papain has been clarified by using site-directed mutagenesis. Both wild-type papain and an… Expand
Charge is the major discriminating factor for glutathione reductase versus trypanothione reductase inhibitors.
- C. Faerman, S. Savvides, +6 authors P. Karplus
- Chemistry, Medicine
- Bioorganic & medicinal chemistry
- 1 August 1996
Benson et al. (Biochem. J. 1992, 286, 9) reported three novel competitive inhibitors of trypanothione reductase (TR), which were selected to complement a hydrophobic region identified on the TR… Expand
Evidence for the interaction of valine-10 in cystatin C with the S2 subsite of cathepsin B.
- P. Lindahl, D. Ripoll, M. Abrahamson, J. Mort, A. C. Storer
- Chemistry, Medicine
- Biochemistry
- 12 April 1994
The interactions between wild-type or mutant recombinant forms of human cystatin C and rat cathepsin B were characterized by measuring progress curves for substrate hydrolysis in the presence of… Expand
Immunomodulatory effect of Achyrocline satureioides (LAM.) D.C. aqueous extracts
- A. L. Santos, D. Ripoll, N. Nardi, V. L. Bassani
- Biology, Medicine
- Phytotherapy research : PTR
- 1 February 1999
The immunomodulatory activity of aqueous extract from Achyrocline satureioides, prepared using heating, was investigated with a mitogen‐induced cell proliferation assay and IL‐2 secretion in BALB/c… Expand
P63 Modified Atmosphere Package for 'Bravo de Esmolfe' Apple
- A. Rocha, D. Ripoll, M. G. Barreiro, A. Morais
- Engineering
- 2000
Bravo de Esmolfe' is a national apple variety which unique organoleptic characteristics make it a produce of excellency among consumers and its price may reach high values. The aim of this work was… Expand