D. R. Voellmy

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The regional levels' profile of human beta-endorphin (beta h-EP) was studied in the brainstem and the cerebellum of 16 infant victims of "Sudden Infant Death Syndrome" and other death causes. An immunoaffinity chromatography procedure based on a monoclonal antibody directed specifically against the N-terminus of beta-EP was used to extract this peptide from(More)
Metastatic melanoma was staged in 15 patients using whole-body positron emission tomography (PET) and the radiopharmaceutical 2-fluorine-18-fluoro-2-deoxy-D-glucose (FDG). PET correctly demonstrated 30 metastases in lung, brain, pancreas, nasal cavity, skin and subcutaneous tissue, and lymph nodes. It detected 97% of all metastases exceeding its spatial(More)
UNLABELLED This study describes a comparison of simulated planar positron coincidence scintigraphy (PCS) with PET in the whole-body staging of patients with malignant melanoma using 2-18F-fluoro-2-deoxy-D-glucose (FDG). METHODS In 55 patients with either known metastatic or newly diagnosed malignant melanoma, whole-body PET scanning was performed on a(More)
A two-site immunoradiometric assay for the highly specific direct quantitation of nonacetylated beta h-EP in crude brain tissue samples has been developed with a detection limit of 10 fmol per well. The assay used two different antibodies with distinct specificities: a polyclonal rabbit anti-beta h-EP antibody binding between the middle portion and the(More)
The methodology and outcome of a hands-on workshop for the evaluation of PACS (picture archiving and communication system) software for a multihospital PACS project are described. The following radiological workstations and web-browser-based image distribution software clients were evaluated as part of a multistep evaluation of PACS vendors in March 2001:(More)
The aim of the present study was to compare the diagnostic value of spiral CT with that of conventional CT in hilar pathologies. Initially, we determined the minimum amount of contrast material necessary which still produced a good enhancement of the pulmonary vessels. After testing with 20 patients, we found that a bolus of 60 ml injected at a rate of 6(More)
The number of CT images increased significantly when 16-row multi-detector CT scanners (MDCT) were introduced. The purpose of this study is to quantify the total data management cost of MDCT and to identify cost drivers. An activity-based costing (ABC) method was used to analyze cost drivers in MDCT data management. Changing from 4-row to 16-row CT, mean(More)
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