D. R. Kaulen

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The bacterial mass, brucellar protective antigen and lipopolysaccharide (LPS) obtained from B. melitensis stimulated the formation of endogenous colonies in the spleen of mice belonging to different strains, subjected to irradiation in sublethal doses. The maximum stimulating effect was observed when the antigens were introduced 24 hours prior to(More)
The wr i t e r s showed previously that lymphocytes activated by antilymphocytic globulin (A LG) l ibera te a soluble fac tor (stem cel l inhibitory factor , SCIF), which depresses the ability of bone m ar ro w and spleen s tem cel ls to form hematopotetic colonies [2, 4, 7]. Considering that me diators of ce l lu la r immunity (lymphokines) play an(More)
The treatment of tumour and lymphoid cells of mice with 3M KC1 solution having high ionic strength, nonionic detergent and by subsequent freeze-thawing resulted in obtaining serologically active H-2 antigen preparation capable of specifically blocking the cytotoxicity of H-2 antisera. The antigenic activity of the preparations thus obtained depended on the(More)
Mycoplasma arthritidis was shown not to affect endogenous colony formation in lethally irradiated BALB/c mice. The number of endogenous foci in mice irradiated in sublethal doses and infected withM. arthritidis was sharply increased when the mycoplasma was injected 24 h before or 4 h after irradiation. Mixed infection of (C57BL/6×A/Sn)F1 mice resistant to(More)
It was demonstrated in this work that rabbit antimouse serum against the aggregated immunoglobulins (RAAS) and mouse serum against the aggregated mouse immunoglobulins (MAAS) inhibited the rosette-forming B-cells (RFC) on the 5th day after the immunization of mice CBA with SRBC in a dose of 5 X 10(-8) cells in vitro in 1:20--1:80, and 1:10--1:40 dilutions(More)
The treatment in vitro of bone marrow cells in mice by phytohemagglutinin, concanavaline, or antilimphocytic globulin resulted in the suppression of exogenous hemopoietic colonies in the spleen of lethally irradiated (830r) syngenic recipients, whereas lipopolysaccharide, tuberculin, anti-theta serum or nati-gamma-globulin serum exerted no influence on the(More)
Experiments on mice of nine strains with different H-2 genotypes showed that a predisposition to anaphylaxis at the stage of formation of IgG1 and IgE antibodies and sensitivity of the skin to passive anaphylaxis and to histamine are independent characters, interaction between which and with other factors form the overall predisposition to immediate allergy.