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BACKGROUND The aetiology of the learning difficulty in tuberous sclerosis is debated. It may be related to the amount of tubers in the brain or caused by the infantile spasms that occur in early life. AIMS To examine the relative contributions to final intelligence (IQ) made by both cerebral tubers and infantile spasms. METHODS As part of an(More)
OBJECTIVES (1) In a population-based study of tuberous sclerosis (TSC), to identify the number of patients presenting with symptomatic giant cell astrocytomas (GCAs); (2) within a subset of this population, to identify the number who would be diagnosed with GCAs on predetermined radiological criteria. METHODS Patients with TSC in Wessex (a geographical(More)
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