D P Bobon

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The AMDP-System has been developed in Europe by the Association for Methodology and Documentation in Psychiatry the standardised documentation of psychiatric files and for the measurement of change in drug trials. It is increasingly used in the French-speaking and German-speaking countries by clinical psychopharmacologists for teaching classical German(More)
Unlike conventional antidepressants, rolipram (a new approach in the treatment of depression) stimulates both the presynaptic and the postsynaptic component of monoaminergic transmission. Several double blind trials are under way to assess the clinical efficacy and safety of this compound. The present study was a randomized, 4-week interindividual double(More)
The AMDP-System, elaborated by the Association for Methodology and Documentation in Psychiatry, comprises three anamnestic forms and two rating scales on present psychopathological and somatic state. Its success is increasing in the German-speaking and French-speaking countries. The author's thesis bears among others on the following aspects: importance of(More)
The 4th and 5th forms of the AMDP-System consist of a Psychopathology Scale (100 + 15 items) and of a Somatic Scale (40 + 7 items); the total duration of the interview and filling out is 45 to 60 mn. On the basis of a decade of research done or initiated in Liège, the French-speaking section of the AMDP has contributed to the System with several(More)
The Spanish translation and adaptation of the 17-item Scale extracted from the francophone extension of the AMPD scales, the AMPD-AT, has been filled out in 120 anxious, depressed and other psychiatric patients along with numerous other rating scales measuring anxiety (Hamilton, Zung, STAI, VAS), depression (Hamilton, VAS), and global psychopathology(More)
A total of 95 schizophrenic or manic patients received zuclopenthixol (cis(Z)-clopenthixol) either intramuscularly or orally during a period of 2 to 4 weeks in mean daily doses of 25 mg (i.m.) or 75 mg (p.o.). They were rated with the CGI, VAS, MSS, BPRS, and AMDP scales. Zuclopenthixol proved to be a potent antimanic, anti-aggressive and antidelusional(More)
Ten psychiatrists have independently rated the clinical profile of fluoxetin (Prozac) at the daily dose of 20 mg according to a "Stars of Liège" model comprising three parameters of therapeutic activity (antidepressant, psychostimulant and anxiolytic) and three parameters of side-effects (anticholinergic, sedative and hypotensive). Each parameter, graduated(More)
The efficacy and tolerance of the first thienodiazepine, clotiazepam, is well established but its clinical spectrum and the possibility of a rebound effect upon its cessation needed further research. Moreover, the validity of the AMDP Anxiety scale had been tested but not yet its sensitivity to change. Clotiazepam was given in an "open" design to 42 anxious(More)