D. Noe

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Quantitative experimental data from studies of intracellular processing and transport of secretory and membrane proteins are only rarely evaluated using kinetic modelling. Instead, the analysis of such data is usually limited to calculating either the apparent half-life or the transit time. Neither of these parameters accurately measures rates of cellular(More)
Trained weight lifters lift heavy loads without a concomitant degree of acute low-back injuries. To study the process by which large loads are lifted with minimal injury, integrated electromyographic signals were recorded from four large muscle groups: gluteus maximus, quadriceps, latissimus dorsi, and erector spinae in 4 weight lifters and 11 asymptomatic(More)
Endpoints in aquatic toxicity tests can be measured using a variety of measurement scales including dichotomous (survival), continuous (growth) and count (number of young). A distribution is assumed for an endpoint and analyses proceed accordingly. In certain situations, the assumed distribution may be incorrect and this may lead to incorrect statistical(More)
Females are generally expected to be selective when choosing their social and sexual partners. In a previous laboratory study, female prairie voles (Microtus ochrogaster) showed significant social and sexual preferences for males with longer microsatellite DNA within the avpr1a gene encoding the vasopressin 1a receptor, as predicted if females select mates(More)
Historically, death is the most commonly studied effect in aquatic toxicity tests. These tests typically employ a gradient of concentrations and exposure with more than one organism in a series of replicate chambers in each concentration. Whereas a binomial distribution commonly is employed for such effects, variability may exceed that predicted by binomial(More)
Electromyographic signals (EMG) from surface electrodes over the vastus medialis, rectus femoris and vastus lateralis were monitored during isometric knee extension for 10 TKA patients and 6 control subjects. No significant side-to-side differences in normalized EMG signals from any of the monitored muscles were found when the left and right legs of the(More)
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