Learn More
The p90 ribosomal S6 kinase (RSK) family is a group of highly conserved Ser/Thr kinases that promote cell proliferation, growth, motility and survival. As they are almost exclusively activated downstream of extracellular signal-regulated kinases 1 and 2 (ERK1/2), therapeutic intervention by RSK inhibition is less likely to produce such severe side effects(More)
Geiger-mode Avalanche Photodiodes (G-APD) bear the potential to significantly improve the sensitivity of Imaging Air Cherenkov Telescopes (IACT). We are currently building the First G-APD Cherenkov Telescope (FACT) by refurbishing an old IACT with a mirror area of 9.5 square meters and construct a new, fine pixelized camera using novel G-APDs. The main goal(More)
  • F Temme, M L Ahnen, +29 authors A Wilbert
  • 2015
The First G-APD Cherenkov Telescope (FACT) is an Imaging Air Cherenkov Telescope located on the Canary Island of La Palma. It is the first of its kind which uses Geiger-mode Avalanche Photo Diodes (G-APDs) as photosensors to detect the Cherenkov radiation emitted from secondary particles in a high-energy gamma-ray air shower. A new analysis chain has been(More)
  • J. Buß∗b, M. L. Ahnen, +15 authors J. Buß
  • 2015
The First G-APD Cherenkov Telescope (FACT) is the first operational telescope of its kind, employing a camera equipped with silicon photon detectors (G-APD aka. SiPM). SiPMs have a high photon detection efficiency (PDE), while being more robust to bright light conditions than the commonly used photo-multiplier tubes. This technology has allowed us to(More)
Within the FACT project, we construct a new type of camera based on Geiger-mode avalanche photodiodes (G-APDs). Compared to photomultipliers, G-APDs are more robust, need a lower operation voltage and have the potential of higher photon-detection efficiency and lower cost, but were never fully tested in the harsh environments of Cherenkov telescopes. The(More)
  • 1