D Mahaboob Valli

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Metabolic syndrome is a cluster of risk factors that lead to cardiovascular morbidity and mortality. Recent studies linked metabolic syndrome and several types of cancer. Although metabolic syndrome may not necessarily cause cancer, it is linked to poorer cancer outcomes including increased risk of recurrence and overall mortality. This review tends to(More)
Background:Hypoxia and the subsequent activation of hypoxia-inducible factor-2α (HIF2α) contribute to the progression of a variety of cancers. However, their role in the generation of renal cell carcinoma-derived stem cells has not been fully addressed.Methods:A sphere formation assay, cell proliferation, RT–PCR, western blot, FACS, immunohistochemistry and(More)
Nucleophosmin (NPM1) is a ubiquitous multifunctional phosphoprotein with both oncogenic and tumor suppressor functions. Mutations of the NPM1 gene are the most frequent genetic alterations in acute myeloid leukemia (AML) and result in the expression of a mutant protein with aberrant cytoplasmic localization, NPMc+. Although NPMc+ causes myeloproliferation(More)
In this work, we demonstrate the use of a Field Programmable Gate Array (FPGA) as a physical platform for realizing chaotic delay differential equations (DDE). Moreover, using our platform, we also experimentally study the synchronization between two time delayed systems. We illustrate two different experimental approaches – one is hardware co-simulation(More)
Today’s vehicles include a complex symbiosis of intelligent electronic systems and integrated mechanical structures. In-vehicle networks provide an efficient method of communication between the various electronic components in an automobile. The communication protocols discussed in this paper are Local Interconnect Network (LIN), Controller Area Network(More)
AIMS To investigate, within the domain of the doctor-patient relationship in an Artificial Insemination Centre, whether not only a precise aetiological diagnosis about the physical impairment, but also an accurate analysis of the request of help by the infertile couple is actually performed. If the hidden meanings underlying many patients' requests for help(More)
The AML1/ETO fusion protein found in acute myeloid leukemias functions as a transcriptional regulator by recruiting co-repressor complexes to its DNA binding site. In order to extend the understanding of its role in preleukemia, we expressed AML1/ETO in a murine immortalized pluripotent hematopoietic stem/progenitor cell line, EML C1, and found that genes(More)
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