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OBJECTIVE To study the association of chromosomal polymorphic variations with infertility and subfertility. DESIGN A comparative case-controlled association study using cytogenetic techniques to compare the frequency of chromosomal variations in infertile individuals versus fertile controls. SETTING Department of Infertility Management and Assisted(More)
BACKGROUND Breast duct microendoscopy is a new technique that allows direct visualization of the mammary ductal epithelia and has the potential to provide greater accuracy in the diagnosis of benign and malignant breast conditions. We have already established the feasibility of BDME on mastectomy specimens and in patients both under general and local(More)
BACKGROUND The overall incidence of male breast cancer is around 1% of all breast cancers and is on the rise. In this review we aim to present various aspects of male breast cancer with particular emphasis on incidence, risk factors, patho-physiology, treatment, prognostic factors, and outcome. METHODS Information on all aspects of male breast cancer was(More)
INTRODUCTION The use of acellular dermal matrix (ADM) has transformed the technique of implant-based breast reconstruction. It offers the option of a one-stage procedure and is felt to have benefits in cosmetic outcome but the medium and long-term outcomes are unknown. METHODS All cases where ADM was used in a breast reconstructive procedure in the(More)
AIMS The aims of this study were to evaluate the sensitivity, specificity; accuracy, usefulness and role of core biopsy imprint cytology (CBIC) in the one-stop breast clinic in a District General Hospital. METHODS A retrospective study was made of symptomatic patients attending a district general hospital one-stop clinic over a five year period where a(More)
OBJECTIVE To analyze clinical implications of the thoracodorsal nerve division in the latissimus dorsi musculocutaneous flap breast reconstruction. PATIENTS AND METHODS Prospective cohort study was conducted on 29 patients. Breast reconstruction with latissimus dorsi musculocutaneous flap was performed unilaterally in 20 patients or bilaterally in 9 women(More)
Gigantomastia by definition means bilateral benign progressive breast enlargement to a degree that requires breast reduction surgery to remove more than 1800 g of tissue on each side. It is seen at puberty or during pregnancy. The etiology for this condition is still not clear, but surgery remains the mainstay of treatment. We present a unique case of(More)
INTRODUCTION Breast conserving surgery (BCS) aims to remove a breast cancer completely and obtain clear margins. Complete excision is essential to reduce the risk of local recurrence. The ClearEdge™ (CE) imaging device examines margins of excised breast tissue intra-operatively. The aim of this study was to investigate the potential of the device in(More)