D M Girdaladze

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A case of hairy-cell leukemia (HCL) has been described in which the cells of the pathological clone in the course of time lost their surface immunoglobulins and retained membrane markers associated with the T-lymphoid series. It has been suggested that this change in the immunological phenotype of the cells may lead to an erroneous diagnosis of T-cell HCL.
Chronic lymphocytic leukaemia (CLL) is a lymphoproliferative disease characterised by accumulation of monoclonal CD19+CD5+CD23+ lymphocytes in the peripheral blood and bone marrow. CLL is the most common type of the adult leukemia in the Western world. The disease is incurable, albeit there are new molecular and immunotherapy methods currently available in(More)
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