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The long-term immunogenicity and protection provided by a plasma-derived hepatitis B vaccine was determined in a cohort of susceptible Chinese adolescents who were immunized in 1986. Ninety-five children, aged 13 to 15 years, received three vaccine doses (at 0, 1, and 2 months), and during subsequent annual follow-ups for 5 years, their serological markers(More)
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