D Lakmali Amarasiri

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BACKGROUND Asthmatics are known to have esophageal hypomotility. Vagal hypofunction and prolonged intra-esophageal acidification cause esophageal hypomotility. The contribution of gastroesophageal reflux (GER) and vagal function to esophageal motility in asthmatics is unclear. We studied the relationship between esophageal motility, GER and vagal function(More)
INTRODUCTION Gastro-oesophageal reflux disease (GORD) is the pathological reflux of gastric contents into the oesophagus. The oesophagus and the upper respiratory tract have a common origin from the foregut. There is increasing evidence for multiple associations of GORD with the upper respiratory tract. OBJECTIVES To study the presence of and association(More)
The editorial team of Digestive Diseases and Sciences wishes to acknowledge and thank the individuals whose names appear in the following list of reviewers for calendar year 2014. Manuscript reviews by these research scientists, clinical investigators, and members of the editorial board, are fundamental to the excellence and integrity of the journal and are(More)
The editorial team of Digestive Diseases and Sciences (DDS) wishes to acknowledge and thank the individuals whose names appear in the following list of reviewers for calendar year 2013. Manuscript reviews by these research scientists, clinical investigators, and members of the editorial board, are fundamental to the excellence and integrity of the journal(More)
BACKGROUND Gastro-esophageal reflux disease (GERD) predisposes to airway disease through a vagally-mediated esophago-bronchial reflex. This study investigates this vagal response to esophageal acid perfusion. METHODS 40 asthmatics with mild stable asthma participated. Each subject underwent spirometry and autonomic function testing (valsalva maneuver,(More)
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