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A heterologous radioimmunoassay system was developed for the determination of circulating IGF-II concentrations in swine. The assay utilized a monoclonal antibody against human IGF-II (Amano Intl. Ez, VA) and bovine IGF-II (Monsanto Co., MO) as the cold standard and iodinated ligand. Serial dilutions of acid-ethanol extracted normal swine sera resulted in a(More)
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