D. K. Harrison

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1 School of Engineering Science and Design, Glasgow Caledonian University, G4 0BA Glasgow, Scotland, UK. Abstract This paper describes the use of Simulink Target for Real-Time Linux (ST-RTL) to control over a network a horizontal driven inverted pendulum. ST-RTL is an application developed to provide a cost-effective alternative to the expensive real-time(More)
The response of six healthy young adults to tuberculin skin testing was studied. Five subjects developed a typical delayed-type hypersensitivity reaction to PPD with a local rise in skin temperature, and the sixth showed a less intense response; a considerable increase in blood flow velocity was seen in all reactions. All subjects showed a fall in pH in the(More)
OBJECTIVES To study the relationship between carotid plaque morphology and the degree of stenosis on Duplex ultrasonography and symptoms. DESIGN Prospective open clinical study. METHODS 2,590 patients with 5,180 carotid arteries were scanned, 4,560 were initially analysed in terms of symptoms but 54 were excluded, leaving a total of 4,258. RESULTS(More)
A variable model of venous hypertension was used to examine the immediate effect on skin oxygenation and blood flow. Measurements were carried out using laser Doppler flowmetry, transcutaneous oximetry and both macro- and micro-lightguide spectrophotometry to measure haemoglobin saturation (SO2). Assessments were performed on 20 normal subjects and in ten(More)
1. Multiwire surface electrodes were used to measure local hydrogen clearance curves and tissues PO2 in the sartorius muscle in dogs under resting conditions and during stimulation of the muscle at 1, 2, 4, 8 and 20 Hz via the femoral nerve. Tissue oxygen supply was assessed by means of PO2 histograms; evaluation of the initial slopes of the hydrogen(More)
Helicases move on DNA via an ATP binding and hydrolysis mechanism coordinated by well-characterized helicase motifs. However, the translocation along single-stranded DNA (ssDNA) and the strand separation of double-stranded (dsDNA) may be loosely or tightly coupled. Dda is a phage T4 SF1B helicase with sequence homology to the Pif1 family of helicases that(More)
BACKGROUND Surgical-site infections (SSIs) are common after major abdominal and groin bypass surgery. Tissue oxygen tension has been shown to predict these infections accurately. This study assessed whether a non-invasive measurement of tissue oxygenation, tissue oxygen saturation as measured by spectrophotometry, was as accurate. METHODS Fifty-nine(More)
The reduction of peripheral blood flow, which occurs during shock or in patients with occlusive arterial disease of the lower limb is accompanied by an increase in hydrogen ion activity in tissue cells. If this change could be measured, it could possibly be used as an indicator of tissue perfusion in such patients. Investigations have been carried out into(More)
Recently lightguide spectrophotometry (LGS) has been investigated for assessing bowel mucosal oxygenation and may prove helpful in the diagnosis of bowel ischaemia. This pilot study explores the use of LGS and laser Doppler flowmetry (LDF) to measure SO2 and perfusion in the bowel during key stages of colon surgery. SO2 and perfusion in the mucosal and(More)