D. K. Chitre

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OBJECTIVE To evaluate RA-1, a standardized plant extract formulation, traditionally considered a safe, effective antiarthritic in the Asian-Indian Ayurvedic medicinal system. METHODS One hundred eighty-two patients with active-on-chronic rheumatoid arthritis (RA) participated in a 16 week randomized, double blind, placebo controlled, parallel efficacy(More)
BACKGROUND The ancient Indian (Asian) Ayurvedic medicinal system uses herbomineral drugs to treat arthritis. Despite centuries of use, very few have been tested by drug trials. RA-11 (ARTREX, MENDAR), a standardized multiplant Ayurvedic drug (Withania somnifera, Boswellia serrata, Zingiber officinale, and Curcuma longa) is currently used to treat arthritis.(More)
OBJECTIVE To study the physiological and behavioral response to pain. METHODS 80 healthy neonates requiring bilirubin estimation, blood sugar etc, were randomly assigned to receive a venous puncture. All parameters were recorded 10 minutes prior, during and 10 minutes after the procedure. Evaluated NIPS score and RR. HR, NIBP and O2 saturation observed on(More)
Rheumatoid arthritis is a chronic crippling disease, where protein-based tumor necrosis factor-alpha (TNF-α) inhibitors show significant relief, but with potentially fatal side effects. A need for a safe, oral, cost-effective small molecule or phyto-pharmaceutical is warranted. BV-9238 is an Ayurvedic poly-herbal formulation containing specialized(More)
Most of the synthetic chemotherapeutic agents available today are immunosuppressants, cytotoxic, and exert variety of side effects that are particularly evident in cancer chemotherapy. Botanical based immunomodulators are often employed as supportive or adjuvant therapy to overcome the undesired effects of cytotoxic chemotherapeutic agents and to restore(More)
OBJECTIVE OF THE STUDY To clinically validate the efficacy and safety of herbal cough formula CORSHE-E of ayurvedic origin. PROCEDURE An open label, uncontrolled clinical study was done on thirty patients with history of cough. The patients were given the cough syrup after they were enrolled in the study and were followed up for a period of seven days.(More)
Organizations apply data or information security only in terms of protecting their network from intruders (e.g. hackers) but with growing amount of sensitive data and rapid growth in the sizes of organizations (e.g. due to globalization), rise in number of data points (machines and servers) and easier modes of communication, sometime accidental or even(More)
Genetic algorithms (GA) are search algorithms based on the mechanics of natural selection and natural genetics. Genetic algorithm was developed by John Holland in the 1970's and got popular in the late 1980's. It is based on ideas from Darwinian evolution (Survival of the fittest). This is an evolutionary computational technique and can be used to solve a(More)