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Identification of 9-O acetyl sialoglycoconjugates (9-OAcSGs) as biomarkers in childhood acute lymphoblastic leukemia using a lectin, AchatininH, as a probe
Neoplastic transformation causes changes in cell surface architecture, most notably, aberrant sialylation. Exploiting the restricted specificity of a 9-O acetyl sialic acid (9-OAcSA) binding lectin,… Expand
Development of a simple, blood based lymphoproliferation assay to assess the clinical status of patients with acute lymphoblastic leukemia.
Although childhood acute lymphoblastic leukemia (ALL) is highly responsive to chemotherapy, reliable techniques are needed to determine treatment outcome and predict relapse. Employing a 9-O-acetyl… Expand
Molecular studies of haemoglobin-E in tribal populations of Tripura
A novel method for prognostic evaluation of childhood acute lymphoblastic leukemia
Although childhood acute lymphoblastic leukemia (ALL) is highly responsive to chemotherapy, patients in remission may harbor residual leukemic blasts, the cause of disease persistence and… Expand
A colorimetric assay to evaluate the chemotherapeutic response of children with acute lymphoblastic leukemia (ALL) employing achatininH: a 9-O-acetyl sialic acid binding lectin.
Employing a 9-O-acetyl sialic acid binding lectin, Achatinin(H) (ATNH), we have reported a non-invasive, blood based lymphoproliferation assay which measures the maximal lymphoproliferative dose… Expand
O-acetyl sialic acid binding lectin as a probe for detection of subtle change on cell surface induced during acute lymphoblastic leukemia (ALL) and its clinical application.
- C. Mandal, D. Sinha, V. Sharma, D. Bhattacharya
- Biology, Medicine
- Indian journal of biochemistry & biophysics
- 1 February 1997
A novel probe, a 9-O-acetylated sialic acid binding lectin, namely achatininH (ATNH) has been used for the detection of changes on the cell surface during acute lymphoblastic leukemia (ALL). ATNH… Expand
Effect of Emblica officinalis tannoids on a rat model of tardive dyskinesia.
- S. K. Bhattachary, D. Bhattacharya, A. Muruganandam
- Indian journal of experimental biology
- 19 February 2000
Effect of active tannoid principles of E. officinalis, comprising of emblicanin A (37%), emblicanin B (33%), punigluconin (12%) and pedunculagin (14%), was investigated on a rat model of tardive… Expand