D. Julian M. Davies

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Chimeric antigen receptor (CAR) engineered T-cells occupy an increasing niche in cancer immunotherapy. In this context, CAR-mediated CD3ζ signaling is sufficient to elicit cytotoxicity and interferon-γ production while the additional provision of CD28-mediated signal 2 promotes T-cell proliferation and interleukin (IL)-2 production. This(More)
The growth of health informatics as a discipline has led to an increase in networks of people with similar interests for discussion, learning and sharing. Alongside these community networks, education and training are gaining interest, with more career opportunities and general public seeking information. This paper highlights the experience of the West(More)
Please note that this is an interim report. The final report will be published following the publication of reported casualty data for Great Britain by DfT (expected 25 th June 2015). This is not an official publication of the House of Commons or the House of Lords. It has not been approved by either House or its committees. All-Party Groups are informal(More)
Why does it matter whether a work is fiction or nonfiction? Gregory Currie claims that the distinction is crucial: There can hardly be a more important question about a piece of writing or speech than this: Is it fiction or nonfiction? If the question seems not especially important, that " s because we rarely need to ask it. Most often we know, in advance(More)
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