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Activation likelihood estimation (ALE) meta-analyses were used to examine the neural correlates of prediction error in reinforcement learning. The findings are interpreted in the light of current computational models of learning and action selection. In this context, particular consideration is given to the comparison of activation patterns from studies(More)
OBJECTIVE To systematically evaluate the latent structure of the Hospital Anxiety and Depression Scale (HADS) through reanalysis of previous studies and meta confirmatory factor analysis (CFA). METHOD Data from 28 samples were obtained from published studies concerning the latent structure of the HADS. Ten models were considered, including eight(More)
Object recognition and naming deficits in dementia of the Alzheimer type (DAT) have typically been attributed to deficits in semantic processing, with only a few studies proposing loci of deficits other than semantic. One possible cause of DAT object recognition impairments could involve deficits in processing structural aspects of visually presented items.(More)
BACKGROUND This experiment examines two aspects of delusional cognition that have been reported clinically but not investigated empirically. These are the incorporation of potentially conflicting information into the recall of delusion-related scripts and the type and amount of material produced additional to that presented for recall, referred to here as(More)
Visual object recognition and naming deficits in patients with dementia of the Alzheimer type (DAT) have typically been attributed to deficits in semantic processing. On a visual object naming test, a group of 10 mild, early stage DAT patients (mean MMSE=23.8) were found to suffer from anomia, compared to a group of 10 age-matched control participants. DAT(More)
This paper considers the results of three different methods of encoding visual and motor representations of single sequential character production using three different architectures for the simulation of perceptual and motor processes. Examination of such processes through neural net modelling of the generation of handwritten characters promises to be a(More)
OBJECTIVE As with other chronic physical illness, rates of depressive disorder are high in rheumatoid arthritis (RA). The aim of the current study was to identify distinct trajectories of psychological distress over 10 years in a cohort of RA patients recruited very early in the course of the disease. METHODS Psychological distress as measured by the(More)
INTRODUCTION Bleuler's concept of loosening of associations which he believed epitomised psychotic thinking can manifest as overinclusion (merging of semantic categories) on semantic categorisation tasks. Overinclusion is explained by excessive activation within the semantic memory network to subordinate features with low associative strength. Therefore(More)