D J Fawthrop

Learn More
Induced differentiation of cultured astrocytes to a process-bearing morphology has been described with a variety of agents known to increase intracellular cyclic AMP. The ionophores A23187 and ionomycin were found to induce a reversible change in astrocyte morphology to a process-bearing form. Cell death also occurs following exposure to either A23187 or(More)
In a previous paper we have shown that the calcium ionophores, A23187 and ionomycin, induce a morphological differentiation of cultured astrocytes to a process-bearing form. As A23187 is known to induce the turnover of inositol phospholipids in astrocytes, and this response is dependent on extracellular calcium, we examined the morphological effects of(More)
  • 1