D J Dorahy

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There is general consensus that matrix metalloproteinases are involved in tumour progression. We show herein that inhibition of integrin avb6 expression in colon cancer cells suppresses MMP-9 secretion. This integrin-mediated event is dependent upon direct binding between the b6 integrin subunit and extracellular signal-regulated kinase 2. Targetting either(More)
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