D. Guy

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The surface of single cells isolated from solid tumours by either a mechanical or an enzymatic method have been compared, using lactoperoxidase-catalyzed radioiodination of the tyrosine-containing proteins. Qualitatively, the patterns of surface labelling were similar, and duplicate experiments indicated that each method of isolation gave reproducible(More)
Present evidence suggests that the cell surface has an important role in metastasis. To examine this idea further, the surface properties of single cells isolated from the primary growths of a liver-metastasizing (ML) and a non-metastasizing (NML) lymphosarcoma were compared for adhesion to cell monolayers, cytopherometry, isoelectric focusing, adhesion to(More)
Methods have been developed which isolate single viable cells from the primary growths of two tumour systems (a lymphosarcoma and a carcinoma) and their secondary deposits. Subsequent comparisons of the surface-membrane structure of pairs of these primary and secondary cells, using lactoperoxidase-catalysed radioiodination coupled with polyacrylamide-gel(More)
The genetic basis of resistance to Rhynchosporium commune was investigated in a winter barley mapping population derived from a cross between cultivars Saffron (moderately susceptible) and Retriever (moderately resistant). Resistance was assessed in field trials through total infection (measured using qPCR), and visible disease symptoms. Phenotypic(More)
The Friesian breed makes a substantial contribution to beef production in Great Britain. The value of selection for beefing characteristics has been studied based on the discounted gene flow technique (M C C LIN T OCK and C UNNINGHAM). The technique has been adapted to consider the use of crossbred females as beef suckler cows. The selection for beef can(More)
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