D Goldstein

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OBJECTIVE To evaluate reasons for telling or not telling patients about a diagnosis of Alzheimer's disease and to assess the effect of such a decision on patients, families, physicians, and the health care system. QUALITY OF EVIDENCE MEDLINE was searched from January 1966 to December 1999 using the key words "Alzheimer's disease" or "dementia" and "truth(More)
Address: 1Baylor Institute for Immunology Research, Dallas, TX, USA, 2Baylor Health Care System, Dallas, TX, USA, 3Dept. of Pediatrics, UTSW, Dallas, TX, USA, 4University of North Carolina, Chapel Hill, NC, USA, 5Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA, 6Duke Institute for Genome Sciences and Policy, Duke University,(More)
Understanding how human genetic variation impacts individual response to immunogens is fundamental for rational vaccine development. To explore host mechanisms involved in cellular immune responses to the MRKAd5 human immunodeficiency virus type 1 (HIV-1) gag/pol/nef vaccine tested in the Step trial, we performed a genome-wide association study of(More)
Many genetic disorders in the Irish Traveller population follow a clan structure with certain disorders occurring only in specific clans or regions. Identification of disease genes can be simplified by comparing the genetic data of multiple patients with the same condition. However, this can be complicated for heterogeneous disorders whereby the same(More)
The Ulster Medical Society grants to all users on the basis of a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International Licence the right to alter or build upon the work non-commercially, as long as the author is credited and the new creation is licensed under identical terms. Behcet's disease (BD) is a complex, multifactorial rare disease,(More)
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