D. Depierre

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The present study examines the possibility of correlation between free serum and urinary total hydroxyproline and whether this correlation can be applied to clinical conditions. The correlation between the two indices was 0.80 (P less than 0.001) in 18 patients, mostly suffering from malignant disease. On comparing the same measurements in 37 patients, all(More)
EARLY DETECTION of tumour metastasis is important for the clinical oncologist, since the therapeutic modalities may be influenced by the tumour stage. For some common tumours the first metastases are often in bone. The symptoms of skeletal metastasis either appear late or lack specificity. Various biochemical markers have been put forward for the early(More)
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