D. B. Varley

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AIMS To estimate the current and future economic burdens of Type 1 and Type 2 diabetes in the UK. METHODS A top-down approach was used to estimate costs for 2010/2011 from aggregated data sets and literature. Prevalence and population data were used to project costs for 2035/2036. Direct health costs were estimated from data on diagnosis, lifestyle(More)
The allocation of office space in any large institution is usually a problematical issue, which often demands a substantial amount of time to perform manually. The result of this allocation affects the lives of whoever makes use of the space. In the higher education sector in the UK, space is becoming an increasingly precious commodity. Student numbers have(More)
BACKGROUND AND AIMS Key information summary is one of the first national shared electronic patient records enabling GPs to share clinical information with unscheduled care providers, including out-of-hours. Implemented during 2013, over 90,000 patient records have been created. This evaluation identified the impact of key information summary on healthcare(More)
BACKGROUND Since 2005, International Committee of Medical Journal Editors (ICMJE) member journals have required that clinical trials be registered in publicly available trials registers before they are considered for publication. OBJECTIVES The research explores whether it is adequate, when searching to inform systematic reviews, to search for relevant(More)
Postmenopausal women with advanced breast cancer recurring/progressing on or after initial (adjuvant or first-line) endocrine therapy may be treated multiple times with one of several endocrine or combinatorial targeted treatment options before initiating chemotherapy. In the absence of direct head-to-head comparisons of these treatment options, an indirect(More)
The field of Genetic Algorithms has grown into a huge area over the last few years. Genetic Algorithms are adaptive methods, which can be used to solve search and optimisation problems over a period of generations, based upon the principles of natural selection and survival of the fittest. This paper describes an innovative tool to introduce the basics of(More)
In many institutions of higher education, office space is a precious commodity and its correct utilisation affects the functioning of the working environment. In academic institutions in particular, there are continuous changes in rooms and/or resources that have a direct impact on the space distribution. Therefore, improving the existing distribution of(More)
BACKGROUND Search filters or hedges are search strategies developed to assist information specialists and librarians to retrieve different types of evidence from bibliographic databases. The objectives of this project were to learn about searchers' filter use, how searchers choose search filters and what information they would like to receive to inform(More)
Recent systematic reviews have reported a positive, although modest, effect of probiotics in terms of preventing common cold symptoms. In this systematic review, the effect of probiotics, specifically Lactobacillus and Bifidobacterium strains, on the duration of acute respiratory infections in otherwise healthy children and adults was evaluated. To identify(More)