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Complex networks are studied across many fields of science. To uncover their structural design principles, we defined "network motifs," patterns of interconnections occurring in complex networks at numbers that are significantly higher than those in randomized networks. We found such motifs in networks from biochemistry, neurobiology, ecology, and(More)
Among the functions of the brain is information storage, which is physically implemented through changes in the strengths of synapses. Experimental investigations have revealed that synapses possess interesting and, in some cases, unexpected properties. Adopting the optimization approach to biology, we describe an information theoretic framework that(More)
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