D. A. Ward

Learn More
In an effort to develop a method of tissue injury which would provide a model for the study of axonal regrowth in adult mammalian central nervous system (CNS), we have analyzed the effects of freezing in the dorsal columns of more than 200 rat spinal cords. The effects of temperature and time of exposure upon the size, shape, distribution and histologic(More)
OBJECTIVE A series of studies examined how various blood ethanol concentrations influenced the effectiveness of a negative punishment procedure in a risk-taking/decision-making task. Based on the animal punishment literature plus the impression that ethanol diminishes the effects of punishment and impairs decision making, it was predicted that individuals(More)
PURPOSE Previously, we mapped the disease locus in the beagle model of autosomal recessive primary open angle glaucoma (POAG) to a 4-Mb interval on chromosome 20, and identified a Gly661Arg variant in ADAMTS10 as the candidate disease-causing variant. The purpose of this study was to test the hypothesis that the Gly661Arg variant of ADAMTS10 causes glaucoma(More)
Two groups, each consisting of six male rats, breathed 21% O2-4% CO2 or 10% O2-4% CO2, respectively, before and after carotid sinus nerve (CSN) transection. Polygraphic recording techniques served to monitor sleep and wakefulness. The effects of these gas mixtures on the sleep-waking pattern (SWP) were studied. The SWPs of the intact and CSN-transected rats(More)
In this paper, the Extended-Domain-Eigenfunction-Method (EDEM) is combined with the Level Set Method in a composite numerical scheme for simulating a moving boundary problem. The liquid velocity is obtained by formulating the problem in terms of the EDEM methodology and solved using a least square approach. The propagation of the free surface is effected by(More)
The purpose of this paper was to determine the efficacy and safety of topical tacrolimus, compared to cyclosporine, for treating keratoconjunctivitis sicca (KCS) in dogs. This study was a two-phase, randomized, controlled, masked clinical trial. Phase 1 evaluated ophthalmic 0.03% tacrolimus in normal dogs. Ocular examinations were performed daily. Phase 2(More)
Photopic and scotopic flash electroretinograms (fERGs) were done on 12 adult captive anesthetized bald eagles (Haliaeetus leucocephalus) following a complete ophthalmic exam. The b-wave amplitude in the bald eagle exceeds that seen in other species when using a similar protocol. This data may be used clinically as a reference for bald eagles undergoing fERG(More)
This letter describes the development of a rogowski coil current and on-chip temperature sensor for evaluating the sag of conductors in high voltage transmission line. A rogowski coil has a air core instead of an iron core. The measurement show excellent linearity with practical no saturation problems. In addition, the rogowski rate highly for electrical(More)
4,6,6-Trimethylcaprolactam antagonised GABAA receptor-mediated contractile responses in guinea-pig isolated ileum, displacing the GABA dose-response curve to the right in a non-parallel manner, and causing a depression of the maximum response. Pentobarbitone not only potentiated the GABAA receptor-mediated contractions but also reversed this non-competitive(More)