D. A. Hedges

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BACKGROUND The objective of this randomized, double-blind study was to compare the efficacy and safety of venlafaxine extended release (XR) and buspirone in outpatients with generalized anxiety disorder (GAD) but without concomitant major depressive disorder. METHOD Male and female outpatients at least 18 years old who met the DSM-IV criteria for GAD and(More)
Although the monoamine oxidase inhibitor phenelzine has proven efficacious in social phobia, the risk of hypertensive crises has reduced its acceptability. The reversible monoamine oxidase inhibitor moclobemide has less potential for such reactions, but its efficacy in this disorder remains unproven. A double-blind, placebo-controlled study was undertaken(More)
This study examined N2 and CO2 components of narcosis by comparing the effects of three levels of PETCO2 [low = 29 mmHg (SD = 4 mmHg), medium = 47 mmHg (SD = 1 mmHg), high = 57 mmHg (SD = 2 mmHg)] at 1 and 6 atm abs in 12 male volunteers. Cognitive and psychomotor performances were examined using a variety of tasks, including a modified Stroop test, an(More)
OBJECTIVE This study aimed to investigate the relationship between (1) onset of the acoustic signal (X1a) and prephonatory phases associated with oscillatory onset and (2) offset of the acoustic signal (X2a) with the postphonatory events associated with oscillatory offset across vocally healthy adults. SUBJECTS AND METHODS High-speed videoendoscopy was(More)
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