D A Adsmond

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The hydrogen-bond connectivity in 39 sulfonamide crystal structures has been deciphered and described using graph set notation. The hydrogen-bond connectivity observed is used to gain information on hydrogen-bond preferences of specific donor and acceptor atoms of related sulfonamide molecules. The amido protons show a greater preference for hydrogen(More)
The crystal structures (determined from single-crystal X-ray diffraction studies) and hydrogen-bond patterns of three crystalline 1,2-dialkyl-3-hydroxy-4-pyridones and their 1:1 formic acid solvates are elucidated. The primary hydrogen-bond connectivities observed are explained by a model that predicts that the best donor bonds to the best acceptor.(More)
1,2-Dialkyl-3-hydroxy-4-pyridones (DAHPs) are iron chelators that are being considered for oral administration for the treatment of anemias. They form 1:1 solvates with formic acid (DAHP-F). The lower DAHP homologues, differing in the alkyl chain length in the 1- and/or 2-positions, have known crystal structures and hydrogen-bond patterns. The main(More)
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