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Following up on recent genome-wide association studies (GWAS) of Crohn's disease, we investigated 50 previously reported susceptibility loci in a German sample of individuals with Crohn's disease (n = 1,850) or ulcerative colitis (n = 1,103) and healthy controls (n = 1,817). Among these loci, we identified variants in 3p21.31, NKX2-3 and CCNY as(More)
4246 Background: The use of monoclonal antibody therapies against growth factor receptors as treatment for malignant tumours is on the increase. The potential usefulness of such therapies may be determined by assessment of the expression level of the receptor. Inter-study variation in the levels of the HER2 and EGFR receptors has been seen in PDACs. This(More)
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