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- Luke Jostins, Stephan Ripke, +103 authors Judy H Cho
- Nature
- 2012
Crohn’s disease and ulcerative colitis, the two common forms of inflammatory bowel disease (IBD), affect over 2.5 million people of European ancestry, with rising prevalence in other populations.… (More)
- Carl A Anderson, Gabrielle Boucher, +110 authors John D Rioux
- Nature genetics
- 2011
Genome-wide association studies and candidate gene studies in ulcerative colitis have identified 18 susceptibility loci. We conducted a meta-analysis of six ulcerative colitis genome-wide association… (More)
- Noortje G M Rossen, Susana Fuentes, +10 authors Cyriel Y. Ponsioen
- Gastroenterology
- 2015
BACKGROUND & AIMS
Several case series have reported the effects of fecal microbiota transplantation (FMT) for ulcerative colitis (UC). We assessed the efficacy and safety of FMT for patients with UC… (More)
- Kirsten Boonstra, Ulrich H. W. Beuers, Cyriel Y. Ponsioen
- Journal of hepatology
- 2012
OBJECTIVE
Studies on the epidemiology of primary sclerosing cholangitis (PSC) and primary biliary cirrhosis (PBC) show variable outcome. We aimed at systematically reviewing the incidence and… (More)
- Tom H. Karlsen, Andre Franke, +29 authors Stefan Schreiber
- Gastroenterology
- 2010
BACKGROUND & AIMS
We aimed to characterize the genetic susceptibility to primary sclerosing cholangitis (PSC) by means of a genome-wide association analysis of single nucleotide polymorphism (SNP)… (More)
- Kirsten Boonstra, Rinse Karel Weersma, +15 authors Cyriel Y. Ponsioen
- Hepatology
- 2013
UNLABELLED
Extensive population-based studies are much needed to accurately establish epidemiology and disease course in patients with primary sclerosing cholangitis (PSC). We aimed to obtain… (More)
- Willem J. Lammers, Henk R van Buuren, +26 authors Bettina E Hansen
- Gastroenterology
- 2014
BACKGROUND & AIMS
Noninvasive surrogate end points of long-term outcomes of patients with primary biliary cirrhosis (PBC) are needed to monitor disease progression and evaluate potential treatments.… (More)
- Mirthe Emilie van der Valk, Marie-Josée J Mangen, +18 authors Bas Oldenburg
- Gut
- 2014
OBJECTIVE
The introduction of anti tumour necrosis factor-α (anti-TNFα) therapy might impact healthcare expenditures, but there are limited data regarding the costs of inflammatory bowel diseases… (More)
- Cyriel Y. Ponsioen, Saskia M. E. Vrouenraets, +6 authors Guido N. J. Tytgat
- Gut
- 2002
BACKGROUND
Median survival of patients with primary sclerosing cholangitis (PSC) has been estimated to be 12 years. Cholangiography is the gold standard for diagnosis but is rarely used in estimating… (More)
- Cyriel Y. Ponsioen, Kwan-hang Lam, A W M van Milligen de Wit, Kees Huibregtse, Guido N. J. Tytgat
- American Journal of Gastroenterology
- 1999
OBJECTIVE:Symptomatic dominant strictures in primary sclerosing cholangitis are often treated with endoscopic stent therapy, but the optimal treatment duration is not well established. After a… (More)