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  • Diane Forget, M. F. Langelier, Cynthia Thérien, Vincent Quoc-Huy Trinh, Benoit Coulombe
  • Biology, Medicine
  • Molecular and cellular biology
  • 2004 (First Publication: 1 February 2004)
  • The topological organization of a TATA binding protein-TFIIB-TFIIF-RNA polymerase II (RNAP II)-TFIIE-promoter complex was analyzed using site-specific protein-DNA photo-cross-linking of gel-purifiedContinue Reading
  • Nicolas Pineault, Valérie Cortin, +4 authors Denis-Claude Roy
  • Biology, Medicine
  • Cytotherapy
  • 2011 (First Publication: 1 April 2011)
  • BACKGROUND AIMS Expansion of hematopoietic progenitors ex vivo is currently investigated as a means of reducing cytopenia following stem cell transplantation. The principal objective of this studyContinue Reading
  • Elizabeth Csaszar, Geneviève Gavigan, +6 authors Peter W. Zandstra
  • Chemistry, Medicine
  • Biotechnology and bioengineering
  • 2009 (First Publication: 1 June 2009)
  • An automated delivery system for cell culture applications would permit studying more complex culture strategies and simplify measures taken to expose cells to unstable molecules. We are interestedContinue Reading
    Graft-versus-host disease (GVHD) is the principal cause of morbidity and mortality after hematopoietic stem cell transplantation. Even the most potent immunosuppressive agents often fail to controlContinue Reading
  • Mireille Guérin, Cynthia Thérien, +4 authors Denis-Claude Roy
  • Medicine
  • 2007 (First Publication: 16 November 2007)
  • Prostate secretory protein 94 (PSP-94) has been shown to exert anti-tumor activity against prostate cancer cells, particularly in the form of PCK3145, a synthetic peptide corresponding to amino acidsContinue Reading